Homelessness is a problem that threatens families and burdens communities.  St. Catherine's homeless services offer shelter and support for the homeless, or for families or individuals who are at risk of becoming homeless. Marillac shelter provides temporary residence and supplemental services to families who have lost their homes. Marillac, Albany County's only shelter designed exclusively for families, not only offers shelter for the homeless, but also provides advocacy and assistance to address conflicts and issues that lead to homelessness.  The program helps secure permanent adequate housing, employment, and other services essential for the welfare of the family (i.e. substance abuse counseling, day care, and mental health counseling). Families in the program may be housed for up to six months at a time. Supplemental, community-based services and counseling are available for families making the transition from a shelter back into the community. 

St. Catherine's newest homeless program, Project HOST, offers housing and health services for homeless singles in Albany and Renssealer counties.

Homeless family services also extend to Columbia County, where St. Catherine’s offers support and intervention services for families at risk of becoming homeless.